How Would You Feel About A Complex Reprogramming Of Your Innate Immune Responses?

Here’s another way to put that question. What kind of people would rush a ‘vaccine’ to market (via EUA) and push it to ever broader swathes of the populace, knowing this, but not doing long term studies of the effects?

I say the responsible parties know this, because studies like this one put them on notice:

Research suggests Pfizer-BioNTech COVID-19 vaccine reprograms innate immune responses

The research actually does more than “suggest” this—it states it as a fact. This is a pre-print, so it’s not peer reviewed. It also dates from May, so when Robert Malone recommends it to your attention I assume that the issue has not been addressed.

The conclusion leaves things up in the air a bit, as far as harm or benefit goes. The point is, the trials that would resolve this issue appear not to have been done. Which is not surprising when we learn things like this:

Anyway …

Researchers in The Netherlands and Germany have warned that Pfizer-BioNTech’s coronavirus disease 2019 (COVID-19) vaccine induces complex reprogramming of innate immune responses that should be considered in the development and use of mRNA-based vaccines.

Jorge Domínguez-Andrés and colleagues say that while the vaccine has been shown to be up to 95% effective in preventing infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and subsequent COVID-19, little is known about the broad effects the vaccine may have on the innate and adaptive immune responses.

In the current study (not peer-reviewed*), the research team … confirmed the efficacy of BNT162b2 vaccination at inducing effective humoral and cellular immunity against several SARS-CoV-2 variants.

However, they also showed that the vaccine altered the production of inflammatory cytokines by innate immune cells following stimulation with both specific (SARS-CoV-2) and non-specific (viral, fungal and bacterial) stimuli.

Following vaccination, innate immune cells had a reduced response to toll-like receptor 4 (TLR4), TLR7 and TLR8 – all ligands that play an important role in the immune response to viral infection.

Neta and colleagues also found that cytokine responses to fungi were increased following vaccination.

The mRNA BNT162b2 vaccine induces complex functional reprogramming of innate immune responses, which should be considered in the development and use of this new class of vaccines,” writes the team.

A pre-print version of the research paper is available on the medRxiv* server. A preprint is a version of a scholarly or scientific paper that precedes formal peer review and publication in a peer-reviewed scholarly or scientific journal.

What do the authors advise?

The researchers say that in combination with strong adaptive immune responses, the reprogramming of innate responses could either contribute to a more balanced inflammatory reaction to SARS-CoV-2 infection or a weakened innate immune response.

The effect of the BNT162b2 vaccination on innate immune responses could also interfere with the responses to other vaccinations, adds the team.

Our findings need to be confirmed by conducting larger cohort-studies with populations with diverse backgrounds, while further studies should examine the potential interactions between BNT162b2 and other vaccines,” concludes Domínguez-Andrés and colleagues.

Let’s see. I think before deploying a ‘vaccine’ you’d normally want to know which alternative it contributes to:  a more balanced inflammatory reaction to the infection or a weakened innate immune response. Inquiring minds and all that. But no.