Do Yourself A Favor--Read This Covid Article
Yesterday we mentioned Dr. Harvey Risch, a very eminent professor of epidemiology at Yale, in the context of an interview with Laura Ingraham: Good Covid News Is Suppressed . Risch has been maintaining not only that the supposed "case" against HCQ is scientifically unfounded but that, in reality, is motivated by politics. HCQ is, he says, the target of a "propaganda war" that has also targeted heroic physicians who try to do their best for their patients.
Later in the day an article to the same effect by Risch appeared--in all places--at Newsweek: The Key to Defeating COVID-19 Already Exists. We Need to Start Using It . I'm providing some highlights, but I urge everyone to read the whole article. In addition to my excerpts, Risch also discusses other issues, including the experience of Brazil and Switzerland as well as other recent studies:
As professor of epidemiology at Yale School of Public Health, I have authored over 300 peer-reviewed publications and currently hold senior positions on the editorial boards of several leading journals. I am usually accustomed to advocating for positions within the mainstream of medicine, so have been flummoxed to find that, in the midst of a crisis, I am fighting for a treatment that the data fully support but which, for reasons having nothing to do with a correct understanding of the science, has been pushed to the sidelines. As a result, tens of thousands of patients with COVID-19 are dying unnecessarily.
Think about that--tens of thousands are the victim of a political hoax, a political propaganda war masquerading as science. Only liberals could get away with this! I'm quite sure Risch understands exactly what he's suggesting.
On May 27, I published an article ... in the world's leading epidemiology journal, ..., demonstrating clear-cut and significant benefits to treated patients, plus other very large studies that showed the medication safety.
Physicians who have been using these medications in the face of widespread skepticism have been truly heroic. They have done what the science shows is best for their patients, often at great personal risk. I myself know of two doctors who have saved the lives of hundreds of patients with these medications, but are now fighting state medical boards to save their licenses and reputations. The cases against them are completely without scientific merit.
Since publication of my May 27 article, seven more studies have demonstrated similar benefit. ...
...
Why has hydroxychloroquine been disregarded?
First, as all know, the medication has become highly politicized. ...
Second, the drug has not been used properly in many studies.
Hydroxychloroquine has shown major success when used early in high-risk people but, as one would expect for an antiviral, much less success when used late in the disease course. ...
... The combination [hydroxychloroquine, azithromycin or doxycycline, and zinc] should be prescribed in high-risk patients immediately upon clinical suspicion of COVID-19 disease, without waiting for results of testing. ...
Third, concerns have been raised by the FDA and others about risks of cardiac arrhythmia, ...
But what the FDA did not announce is that these adverse events were generated from tens of millions of patient uses of hydroxychloroquine for long periods of time, often for the chronic treatment of lupus or rheumatoid arthritis. Even if the true rates of arrhythmia are ten-fold higher than those reported, the harms would be minuscule compared to the mortality occurring right now in inadequately treated high-risk COVID-19 patients. ...
In the future, I believe this misbegotten episode regarding hydroxychloroquine will be studied by sociologists of medicine as a classic example of how extra-scientific factors overrode clear-cut medical evidence. ...